Health Supplements / Life Extension / Life Extension Glutathione, Cysteine & C 100 Vegetarian Capsules
Life Extension Glutathione, Cysteine & C 100 Vegetarian Capsules
Life Extension Glutathione, Cysteine & C 100 Vegetarian Capsules
Glutathione, Cysteine & C 100 Vegetarian Capsules L-cysteine is a conditionally essential amino acid, one of only three sulfur-containing amino acids, the others being taurine (which can be produced from L-cysteine) and L-methionine (from which L-cysteine can be produced in the body by a multi-step process). Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine.1-3 Cysteine also helps synthesize glutathione, the body’s most important intracellular antioxidant and a vital detoxifier.4-7 Glutathione (L-gamma-glutamyl-L-cysteinyl-glycine) is a peptide molecule synthesized in the body from the three amino acids L-glutamic acid, L-cysteine and glycine. Glutathione is one of the body’s most important and powerful antioxidants,8 helping to detoxify xenobiotics.9-12 A major function of vitamin C is to keep glutathione in its reduced form so that it can continue to provide free radical-quenching effects.13-16 Vitamin C, or ascorbic acid, is a white, crystalline, water-soluble substance found in citrus fruits. As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress.17-24 Vitamin C also promotes the absorption of iron, while preventing its oxidation.25,26 Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth.20-22 References 1. Mol Pathol. 2003 Oct;56(5):270-4. 2. Eur J Hum Genet. 2003 Jan;11(1):23-9. 3. Acta Biochim Pol. 2004;51(2):405-13. 4. Biol Chem. 2009 Mar;390(3):191-214. 5. Aviat Space Environ Med. 2008 Dec;79(12):1106-11. 6. Int J Gen Med. 2011 Jan 25;4:105-13. 7. Cardiovasc Toxicol. 2011 Mar;11(1):1-9. 8. Antioxid Redox Signal. 2011 Oct 1;15(7):1957-97. 9. Mutat Res. 2005 Dec 11;591(1-2):74-92. 10. FEBS Lett. 2005 Aug 1;579(19):4081-7. 11. FEBS J. 2009 Jan;276(1):58-75. 12. Toxicol Sci. 2007 Dec;100(2):513-24. Epub 2007 Sep 22. 13. Clin Chim Acta. 2003 Jan;327(1-2):187-8. 14. Proc Natl Acad Sci USA. 1991 Jun 1;88(11):4656-60. 15. Plant Physiol. 2011 Jan;155(1):2-18. 16. Am J Clin Nutr. 2000 May;71(5):1194-200. 17. Biochim Biophys Acta. 2012 Dec;1826(2):443-57. 18. Redox Rep. 2010;15(1):11-9. 19. Adv Nutr. 2011 Mar;2(2):78-88. 20. Altern Med Rev. 2003 Nov;8(4):359-77. 21. J Invest Dermatol. 2002 Apr;118(4):565-72. 22. Radiat Environ Biophys. 2007 Mar;46(1):61-8. 23. Free Radic Biol Med. 2007 Sep 1;43(5):853-9. 24. PLoS Negl Trop Dis. 2012;6(7):e1729. 25. Br J Nutr. 2003 Dec;90(6):1081-5. 26. Am J Clin Nutr. 2006 Oct;84(4):830-4.

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